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Journal of Neuroinflammation: ?Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures

作者:   發(fā)布于:2023年08月09日  點(diǎn)擊量:751
Title:

Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures

Journal:JNI
volume
Year:2012
Abstract

There is increasing interest in astrocyte biology because astrocytes have been demonstrated to play prominent roles in physiological and pathological conditions of the central nervous system, including neuroinflammation. To understand astrocyte biology, primary astrocyte cultures are most commonly used because of the direct accessibility of astrocytes in this system. However, this advantage can be hindered by microglial contamination. Although several authors have warned regarding microglial contamination in this system, complete microglial elimination has never been achieved.

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https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-9-116(如需全文,請(qǐng)聯(lián)系我們)